There were several comments about the Danish study that did not show efficacy for masks in preventing COVID-19. Some readers provided references to other studies that were not placebo controlled, but did show the value from wearing masks. Several readers provided a link from a New York Times critique of the the Danish study, that made similar points of my review.
I do not think anyone is suggesting not to wear masks! Creating a study to demonstrate the value is just hard to do!
As relates to several questions about the prioritization of vaccines, especially to elderly residents of care facilities, many asked if giving this vaccine to the elderly was a good idea.
Any vaccine is a risk benefit decision, and given the remarkable efficacy of the COVID-19 vaccines and the safety profile, even in individuals over 65 years old, I absolutely believe nursing care residents, regardless of age, should take this vaccine.
My only caveat is deciding whether individuals who have already been infected and have evidence of immunity should get the vaccine. This question needs to be addressed as an experimental vaccines against SARS cause enhancement of disease, and a Sanofi vaccine agains dengue caused enhanced disease in individuals who had prior exposure to virus.
Because of this I think everyone should be screened for COVID antibodies before they get the vaccine. At this point I would not deny anyone the vaccine, but those with prior infection need to be monitored for protection and side effects.